MEDICINAL CHEMISTRY

This field is directed towards developing new methodologies and approaches in promoting the status of traditional including herbal medicines and products derived from them into scientifically validated therapeutic agents/biomarkers. Medicinal chemistry is the study that contributes to an understanding of the relationship between molecular structure and biological activity or mode of action. It also includes organic synthesis, biological behaviour, drug design, QSAR, molecular modelling, molecular aspects of drug metabolism, prodrug synthesis and drug targeting. Currently, projects within the program at LHS focus mainly on design, synthesis, and biological evaluation of novel biologically active compounds, molecular modifications of reported series that lead to a significantly improved understanding of their structure-activity relationships (SAR). Computational studies that provide fresh insight into the SAR of compound series that are of current general interest in this field. In addition to that, substantially novel computational chemistry methods with demonstrated value for the identification, optimization, or target interaction analysis of bioactive molecules are also explored.

List of Experts

Updated:: 15/05/2018 [nashrin]